Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype.

Reduced cholinergic function in normal and Alzheimer's disease brain is associated with apolipoprotein E4 genotype.

Apolipoprotein E (ApoE) is a potent risk factor for Alzheimer's disease. Since the loss of cholinergic function in Alzheimer's disease is known to occur at an early stage in the disease we have examined this function in normal subjects with an Apoepsilon4 allele to see if the deficit occur...

書誌詳細
主要な著者:	Allen, S, MacGowan, S, Tyler, S, Wilcock, G, Robertson, A, Holden, P, Smith, S, Dawbarn, D
フォーマット:	Journal article
言語:	English
出版事項:	1997

類似資料

Effect of gender and apolipoprotein E genotype on response to anticholinesterase therapy in Alzheimer's disease.
著者:: MacGowan, S, 等
出版事項: (1998)

Quantitative morphometric analysis of basal forebrain neurons expressing β-nerve growth factor receptors in normal and Alzheimer's disease brains
著者:: Allen, S, 等
出版事項: (1990)

Low affinity nerve growth factor receptor binding in normal and Alzheimer's disease basal forebrain.
著者:: Treanor, J, 等
出版事項: (1991)

Normal beta-NGF content in Alzheimer's disease cerebral cortex and hippocampus.
著者:: Allen, S, 等
出版事項: (1991)

Alzheimer's disease, herpes virus in brain, apolipoprotein E4 and herpes labialis
著者:: Lin, W, 等
出版事項: (1998)

NERVE GROWTH-FACTOR RECEPTOR-BINDING IN NORMAL AND ALZHEIMERS-DISEASE BASAL FOREBRAIN
著者:: Treanor, J, 等
出版事項: (1990)

Alzheimer's disease, herpes virus in the brain, apolipoprotein E4 and herpes labialis. (vol 1, pg 173, 1998)
著者:: Lin, W, 等
出版事項: (1998)

The -491A/T polymorphism of the Apolipoprotein E gene is associated with the ApoEepsilon4 allele and Alzheimer's disease.
著者:: Ahmed, A, 等
出版事項: (1999)

DISTRIBUTION OF NGF RECEPTORS IN CONTROL AND ALZHEIMERS-DISEASE BASAL FOREBRAIN
著者:: Dawbarn, D, 等
出版事項: (1990)

Cloning of a non-catalytic form of human trkB and distribution of messenger RNA for trkB in human brain.
著者:: Allen, S, 等
出版事項: (1994)

Changes in alpha- and beta-secretase in Alzheimer's disease
著者:: Tyler, S, 等
出版事項: (2003)

alpha- and beta-secretase: profound changes in Alzheimer's disease.
著者:: Tyler, S, 等
出版事項: (2002)

Treatment of the cholinergic impairment in Alzheimer's disease
著者:: Wilcock, G
出版事項: (1994)

Apolipoprotein E genotyping in Alzheimer's disease. The UK Alzheimer's Disease Genetic consortium.
著者:: Lovestone, S, 等
出版事項: (1996)

Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease.
著者:: Goedert, M, 等
出版事項: (1989)

Morphometric immunochemical analysis of neurons in the nucleus basalis of Meynert in Alzheimer's disease.
著者:: Allen, S, 等
出版事項: (1988)

Profound and selective loss of catalytic TrkB immunoreactivity in Alzheimer's disease.
著者:: Allen, S, 等
出版事項: (1999)

HLA-DR3 and DQA1*0401: possible risk factors in Alzheimer's disease
著者:: Culpan, D, 等
出版事項: (1999)

The expression of the anti-inflammatory cytokine IL-10 in Alzheimer's disease is independent of IL-10 promoter polymorphisms
著者:: Culpan, D, 等
出版事項: (2002)

Recombinant human nerve growth factor for clinical trials: protein expression, purification, stability and characterisation of binding to infusion pumps.
著者:: Allen, S, 等
出版事項: (2001)

NERVE GROWTH-FACTOR AND OTHER NEUROTROPHINS IN ALZHEIMERS-DISEASE
著者:: Wilcock, G, 等
出版事項: (1994)

Oxidative Insults Are Associated with Apolipoprotein E Genotype in Alzheimer's Disease Brain
著者:: Charles Ramassamy, 等
出版事項: (2000-02-01)

The cholinergic hypothesis of Alzheimer's disease: a review of progress.
著者:: Francis, P, 等
出版事項: (1999)

The blood-brain barrier models to study apolipoprotein E genotypes in Alzheimer’s disease
著者:: Irundika HK Dias, 等
出版事項: (2022-01-01)

The cholinergic hypothesis of Alzheimer's disease: a review of progress - Reply
著者:: Francis, P, 等
出版事項: (1999)

Herpes Simplex Virus Type 1 in the Brain, Apolipoprotein E Genotype and Alzheimer’s Disease
著者:: Uwe Beffert, 等
出版事項: (2020-12-01)

Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.
著者:: Bowen, D, 等
出版事項: (1983)

Immunoglobulin-like domains define the nerve growth factor binding site of the TrkA receptor.
著者:: Holden, P, 等
出版事項: (1997)

Apolipoprotein E genotype, vitamin E, and Alzheimer’s disease prevention
著者:: P. Huebbe, 等
出版事項: (2012-11-01)

Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase.
著者:: Pearson, R, 等
出版事項: (1983)

Apolipoprotein C-I Expression in the Brain in Alzheimer's Disease
著者:: Caroline Petit-Turcotte, 等
出版事項: (2001-12-01)

The effects of apolipoprotein E genotype, α‐synuclein deficiency, and sex on brain synaptic and Alzheimer's disease–related pathology
著者:: Roni Bar, 等
出版事項: (2018-01-01)

Brain tissue banks in psychiatric and neurological research.
著者:: Wilcock, G, 等
出版事項: (1997)

Role of Cholinergic Signaling in Alzheimer’s Disease
著者:: Zhi-Ru Chen, 等
出版事項: (2022-03-01)

Alzheimer′s disease, anesthesia and the cholinergic system
著者:: Mukul C Kapoor
出版事項: (2011-01-01)

Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer’s Disease and Control Mice
著者:: Sandra den Hoedt, 等
出版事項: (2021-10-01)

Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease
著者:: D. Allan Butterfield, 等
出版事項: (2020-05-01)

Apolipoproteins and Alzheimer's pathophysiology
著者:: Manja Koch, 等
出版事項: (2018-01-01)

Brain Cholinergic Mechanisms
著者:: Sukumar eVijayaraghavan, 等
出版事項: (2015-09-01)

Latent herpes simplex virus type 1 in normal and Alzheimer's disease brains.
著者:: Jamieson, G, 等
出版事項: (1991)