Production of SIV-F/HN: a new Lentivirus vector for CF gene therapy

Production of SIV-F/HN: a new Lentivirus vector for CF gene therapy

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Hyde, S, Alton, E, Boyd, A, Davies, JC, Davies, LA, Gill, DR, Griesenbach, U, Hasegawa, M, Inoue, M, Pringle, IA, Sumner-Jones, SG
التنسيق:	Conference item
اللغة:	English
منشور في:	Wiley 2015

مواد مشابهة

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Assessment of F/HN-pseudotyped lentivirus as a clinically relevant vector for lung gene therapy.
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Preparation for a first-in-man lentivirus trial in cystic fibrosis patients
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Towards a first-in-human trial with a pseudotyped lentivirus
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Pre-existing immunity to human parainfluenza virus (hPIV) does not affect rSIV.F/HN-mediated transduction efficiency
حسب: Pytel, K, وآخرون
منشور في: (2016)

Assessment of the air-liquid interface culture model as a tool to validate efficacy of a rSIV.F/HN-CFTR vector
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Rapid determination of rSIV.F/HN lentiviral vector titre
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Expression profile of optimised SIV vector in the mouse lung at early timepoints post-delivery
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Large-scale, high-throughput production of rSIV.F/HN vectors
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حسب: Gill, DR, وآخرون
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Low levels of CFTR gene transfer with F/HN pseudotyped lentivirus are sufficient to generate ion transport correction in airway cell cultures from cystic fibrosis patients
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Genetic medicines for CF: Hype versus reality
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EVALUATION OF SAFETY AND GENE EXPRESSION WITH A SINGLE DOSE OF PGM169/GL67A ADMINISTERED TO THE NOSE AND LUNG OF INDIVIDUALS WITH CF: THE UK CF GENE THERAPY CONSORTIUM "PILOT STUDY"
حسب: Davies, J, وآخرون
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Expression profile of optimised SIV vector in the mouse lung at early timepoints post-delivery
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Assessment of selected media supplements to improve F/HN lentiviral vector production yields
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Lentivirus GM-CSF gene therapy for autoimmune pulmonary alveolar proteinosis
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Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis.
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Update on the UK CF Gene Therapy Consortium Multidoes, non-viral, gene therapy trial
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UPDATE ON THE UK CF GENE THERAPY CONSORTIUM MULTIDOSE, NON-VIRAL, GENE THERAPY TRIAL
حسب: Alton, E, وآخرون
منشور في: (2012)

EVALUATION OF SAFETY AND GENE EXPRESSION WITH A SINGLE DOSE OF PGM169/GL67A ADMINISTERED TO THE NOSE AND LUNG OF INDIVIDUALS WITH CYSTIC FIBROSIS: THE UK CF GENE THERAPY CONSORTIUM "PILOT STUDY''
حسب: Davies, J, وآخرون
منشور في: (2009)

Lentivirus GM-CSF gene therapy ameliorates autoimmune pulmonary alveolar proteinosis
حسب: Lund-Palau, H, وآخرون
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OPTIMISATION OF MOLECULAR ASSAYS FOR CLINICAL TRIAL OF GL67A/PDNA DELIVERY TO NOSE AND LUNG OF CF PATIENTS
حسب: Sumner-Jones, S, وآخرون
منشور في: (2009)

A PHASE 2B DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF NON-VIRAL MEDIATED GENE THERAPY FOR CF
حسب: Alton, E, وآخرون
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Moving lentiviral-based gene therapy into a first-in-man CF trial
حسب: Griesenbach, D, وآخرون
منشور في: (2015)

TOXICOLOGY STUDIES IN SUPPORT OF THE UK CF GENE THERAPY CONSORTIUM'S MULTI-DOSE CLINICAL TRIAL
حسب: Griesenbach, U, وآخرون
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UKCF gene therapy consortium tracking study: Sputum and serum calprotectin are useful novel measurements in CF exacerbation
حسب: Gray, R, وآخرون
منشور في: (2007)

Gene therapy for respiratory diseases; progress and a changing context
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منشور في: (2020)

REPEAT ADMINISTRATION OF GL67A/PGM169 IS FEASIBLE, SAFE, AND PRODUCES ENDOGENOUS LEVELS OF CFTR EXPRESSION AFTER 12 DOSES
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منشور في: (2012)

Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung.
حسب: Alton, E, وآخرون
منشور في: (2014)

Cumulative CFTR expression following repeated aerosol delivery of non-viral pGM169/GL67A formulation to mouse lung
حسب: Alton, E, وآخرون
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Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung
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منشور في: (2014)

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منشور في: (2010)

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High levels of native eGFP detected following F/HN lentiviral vector transduction of a variety of lung models
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