The cytotoxic action of lymphokine activated killer cells upon the human glioma cell line U251 is stimulated by bispecific monoclonal antibody (MoAb) constructs.
The ability of IL-2 stimulated mononuclear cells to kill the human glioblastoma cell line U251 has been investigated. Highest cytotoxic activity was generated in low cell density cultures incubated for 15 days with 250-1000 U/ml IL-2. Sub-optimal killing was noted, with cells only exposed to IL-2 fo...
Hauptverfasser: | Obukhov, S, Gennie, M, Tutt, A, Kemshead, J, Coakham, H, Beverely, P |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
1992
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