Clinical features and molecular analysis of a family with multiple colon tumours and reduced plasminogen activator activity.

A family is reported in which a pair of brothers has developed recurrent venous thromboses, which have been shown in one brother (the proband) to result from a reduced level of tissue plasminogen activator (t-PA) activity. Both brothers have also developed multiple synchronous and metachronous color...

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Bibliographic Details
Main Authors: Tomlinson, I, Beck, N, Williamson, J, Harocopos, C, Mitchell, V, Hodgson, S, Bodmer, W
Format: Journal article
Language:English
Published: 1997