GLP1R and GIPR expression and signaling in pancreatic alpha cells, beta cells and delta cells

Glucagon-like peptide-1 receptor (GLP1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) are transmembrane receptors involved in insulin, glucagon and somatostatin secretion from the pancreatic islet. Therapeutic targeting of GLP1R and GIPR restores blood glucose levels in part by i...

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Hlavní autoři: Shilleh, AH, Viloria, K, Broichhagen, J, Campbell, JE, Hodson, DJ
Médium: Journal article
Jazyk:English
Vydáno: Elsevier 2024