Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients.

Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients.

Induction of cytotoxic CD8 T-cell responses is enhanced by the exclusive presentation of antigen through dendritic cells, and by innate stimuli, such as toll-like receptor ligands. On the basis of these 2 principles, we designed a vaccine against melanoma. Specifically, we linked the melanoma-specif...

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Bibliographic Details
Main Authors: Speiser, D, Schwarz, K, Baumgaertner, P, Manolova, V, Devevre, E, Sterry, W, Walden, P, Zippelius, A, Conzett, K, Senti, G, Voelter, V, Cerottini, J, Guggisberg, D, Willers, J, Geldhof, C, Romero, P, Kündig, T, Knuth, A, Dummer, R, Trefzer, U, Bachmann, M
Format: Journal article
Language:English
Published: 2010

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