The direct catalytic enantioselective synthesis of protected aryl beta-hydroxy-alpha-amino acids.

The direct catalytic enantioselective synthesis of protected aryl beta-hydroxy-alpha-amino acids.

The combination of three reagents-a tridentate pybox ligand (pybox = pyridine bis(oxazoline)), magnesium perchlorate, and Hünig base (iPr 2EtN)-allows the catalytic generation of a chiral glycine enolate from 1 that undergoes highly enantioselective addition to a range of aryl aldehydes 2. The prote...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Willis, M, Cutting, G, Piccio, V, Durbin, M, John, M
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2005

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