Calorimetric dissection of colicin DNase--immunity protein complex specificity.

Calorimetric dissection of colicin DNase--immunity protein complex specificity.

We explore the thermodynamic strategies used to achieve specific, high-affinity binding within a family of conserved protein-protein complexes. Protein-protein interactions are often stabilized by a conserved interfacial hotspot that serves as the anchor for the complex, with neighboring variable re...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Keeble, A, Kirkpatrick, N, Shimizu, S, Kleanthous, K
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	2006

Antzeko izenburuak

The kinetic basis for dual recognition in colicin endonuclease-immunity protein complexes.
nork: Keeble, A, et al.
Argitaratua: (2005)

Structure of the ultra-high-affinity colicin E2 DNase--Im2 complex.
nork: Wojdyla, J, et al.
Argitaratua: (2012)

Thermodynamic dissection of colicin interactions.
nork: Housden, N, et al.
Argitaratua: (2011)

Structure of the ultra-high-affinity colicin E2 DNase-Im2 complex
nork: Wojdyla, J, et al.
Argitaratua: (2012)

Experimental and computational analyses of the energetic basis for dual recognition of immunity proteins by colicin endonucleases.
nork: Keeble, A, et al.
Argitaratua: (2008)

Nuclease colicins and their immunity proteins.
nork: Papadakos, G, et al.
Argitaratua: (2012)

Silencing of DNase Colicin E8 Gene Expression by a Complex Nucleoprotein Assembly Ensures Timely Colicin Induction.
nork: Simona Kamenšek, et al.
Argitaratua: (2015-06-01)

Colicin biology.
nork: Cascales, E, et al.
Argitaratua: (2007)

Thermodynamic consequences of bipartite immunity protein binding to the ribosomal ribonuclease colicin E3.
nork: Walker, D, et al.
Argitaratua: (2003)

Multistep binding of transition metals to the H-N-H endonuclease toxin colicin E9.
nork: Keeble, A, et al.
Argitaratua: (2002)

Colicin translocation across the Escherichia coli outer membrane.
nork: Housden, N, et al.
Argitaratua: (2012)

Energy-dependent immunity protein release during tol-dependent nuclease colicin translocation.
nork: Vankemmelbeke, M, et al.
Argitaratua: (2009)

Metal induced selectivity in phosphate ion binding in E9 DNase.
nork: van den Bremer, E, et al.
Argitaratua: (2005)

In vivo processing of DNase colicins E2 and E7 is required for their import into the cytoplasm of target cells.
nork: Liliana Mora, et al.
Argitaratua: (2014-01-01)

Swimming against the tide: progress and challenges in our understanding of colicin translocation.
nork: Kleanthous, K
Argitaratua: (2010)

Destabilization of the colicin E9 Endonuclease domain by interaction with negatively charged phospholipids: implications for colicin translocation into bacteria.
nork: Mosbahi, K, et al.
Argitaratua: (2004)

A force-activated trip switch triggers rapid dissociation of a colicin from its immunity protein
nork: Farrance, O, et al.
Argitaratua: (2013)

Distinct conformational stability and functional activity of four highly homologous endonuclease colicins.
nork: van den Bremer, E, et al.
Argitaratua: (2004)

Characterisation of a mobile protein-binding epitope in the translocation domain of colicin E9.
nork: Macdonald, C, et al.
Argitaratua: (2004)

The role of electrostatics in colicin nuclease domain translocation into bacterial cells.
nork: Walker, D, et al.
Argitaratua: (2007)

Colicins exploit native disorder to gain cell entry: a hitchhiker's guide to translocation.
nork: Bonsor, D, et al.
Argitaratua: (2008)

O-antigen dependent colicin insensitivity of uropathogenic Escherichia coli
nork: Sharp, C, et al.
Argitaratua: (2018)

A force-activated trip switch triggers rapid dissociation of a colicin from its immunity protein.
nork: Oliver E Farrance, et al.
Argitaratua: (2013-01-01)

Colicins exploit native disorder to gain cell entry: A hitchhiker's guide to translocation
nork: Bonsor, D, et al.
Argitaratua: (2008)

Identification of the catalytic motif of the microbial ribosome inactivating cytotoxin colicin E3.
nork: Walker, D, et al.
Argitaratua: (2004)

Structural design principles for specific ultra-high affinity interactions between colicins/pyocins and immunity proteins
nork: Avital Shushan, et al.
Argitaratua: (2021-02-01)

Clusters in an intrinsically disordered protein create a protein-binding site: the TolB-binding region of colicin E9.
nork: Tozawa, K, et al.
Argitaratua: (2005)

Cell entry mechanism of enzymatic bacterial colicins: porin recruitment and the thermodynamics of receptor binding.
nork: Housden, N, et al.
Argitaratua: (2005)

Structural basis for 16S ribosomal RNA cleavage by the cytotoxic domain of colicin E3.
nork: Ng, C, et al.
Argitaratua: (2010)

Allosteric beta-propeller signalling in TolB and its manipulation by translocating colicins.
nork: Bonsor, D, et al.
Argitaratua: (2009)

Kinetic basis for the competitive recruitment of TolB by the intrinsically disordered translocation domain of colicin E9.
nork: Papadakos, G, et al.
Argitaratua: (2012)

Global structural rearrangement of the cell penetrating ribonuclease colicin E3 on interaction with phospholipid membranes.
nork: Mosbahi, K, et al.
Argitaratua: (2006)

Kinetic basis for the competitive recruitment of TolB by the intrinsically disordered translocation domain of colicin E9
nork: Papadakos, G, et al.
Argitaratua: (2012)

Directional porin binding of intrinsically disordered protein sequences promotes colicin epitope display in the bacterial periplasm
nork: Housden, NG, et al.
Argitaratua: (2018)

Colicin-mediated transport of DNA through the iron transporter FepA
nork: Cohen-Khait, R, et al.
Argitaratua: (2021)

Chemistry and functions of colicins: proceedings/
nork: Hager, Lowell P., et al.
Argitaratua: (1973)

Colicin-Mediated Transport of DNA through the Iron Transporter FepA
nork: Ruth Cohen-Khait, et al.
Argitaratua: (2021-10-01)

Amount of colicin release in Escherichia coli is regulated by lysis gene expression of the colicin E2 operon.
nork: Andreas Mader, et al.
Argitaratua: (2015-01-01)

Colicin E3 cleavage of 16S rRNA impairs decoding and accelerates tRNA translocation on Escherichia coli ribosomes.
nork: Lancaster, L, et al.
Argitaratua: (2008)

Flexibility in the receptor-binding domain of the enzymatic colicin E9 is required for toxicity against Escherichia coli cells.
nork: Penfold, C, et al.
Argitaratua: (2004)