Screening for potential targets for therapy in mesenchymal, clear cell, and dedifferentiated chondrosarcoma reveals Bcl-2 family members and TGFβ as potential targets.

The mesenchymal, clear cell, and dedifferentiated chondrosarcoma subtypes are extremely rare, together constituting 10% to 15% of all chondrosarcomas. Their poor prognosis and lack of efficacious treatment emphasizes the need to elucidate the pathways playing a pivotal role in these tumors. We const...

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Bibliografiska uppgifter
Huvudupphovsmän: van Oosterwijk, J, Meijer, D, Ruler, v, van den Akker, B, Oosting, J, Krenács, T, Picci, P, Flanagan, A, Liegl-Atzwanger, B, Leithner, A, Athanasou, N, Daugaard, S, Hogendoorn, P, Bovée, J
Materialtyp: Journal article
Språk:English
Publicerad: 2013