Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
Monocyte-derived dendritic cells (moDC) have been widely used in cancer immunotherapy but show significant donor-to-donor variability and low capacity for the cross-presentation of tumour-associated antigens (TAA) to CD8(+) T cells, greatly limiting the success of this approach. Given recent develop...
Egile Nagusiak: | Silk, K, Silk, J, Ichiryu, N, Davies, T, Nolan, K, Leishman, A, Carpenter, L, Watt, S, Cerundolo, V, Fairchild, P |
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Formatua: | Journal article |
Hizkuntza: | English |
Argitaratua: |
2012
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