Novel MLH1 duplication identified in Colombian families with Lynch syndrome

Novel MLH1 duplication identified in Colombian families with Lynch syndrome

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Purpose: Lynch syndrome accounts for 2-4% of all colorectal cancer, and is mainly caused by germline mutations in the DNA mismatch repair genes. Our aim was to characterize the genetic mutation responsible for Lynch syndrome in an extensive Colombian family and to study its prevalence in Antioquia....

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Những tác giả chính:	Alonso-Espinaco, V, Giráldez, MD, Trujillo, C, Van Der Klift, H, Muñoz, J, Balaguer, F, Ocaña, T, Madrigal, I, Jones, A, Echeverry, M, Velez, A, Tomlinson, I, Milà, M, Wijnen, J, Carvajal-Carmona, L, Castells, A, Castellví-Bel, S
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2011

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