Radiosensitization by nitric oxide at low radiation doses.

Radiosensitization by nitric oxide at low radiation doses.

Nitric oxide was shown to radiosensitize anoxic V79 and CHO hamster cells and MCF7 and UT-SCC-14 human cells, measuring clonogenic survival and/or DNA damage in vitro at low radiation doses (0.1-5 Gy). Radiosensitization was easily detected after 2 Gy in anoxic V79 cells exposed to 40 ppm ( approxim...

Full description

Bibliographic Details
Main Authors:	Wardman, P, Rothkamm, K, Folkes, L, Woodcock, M, Johnston, P
Format:	Journal article
Language:	English
Published:	2007

Similar Items

Hypoxic radiosensitization by nitric oxide
by: Folkes, L, et al.
Published: (2012)

The role of nitric oxide as a hypoxic cell radiosensitizer
by: Folkes, L
Published: (2013)

Kinetics of the reaction between nitric oxide and glutathione: implications for thiol depletion in cells.
by: Folkes, L, et al.
Published: (2004)

Modification of DNA damage mechanisms by nitric oxide during ionizing radiation.
by: Folkes, L, et al.
Published: (2013)

DNA damage induced by nitric oxide during ionizing radiation is enhanced at replication.
by: Folkes, L, et al.
Published: (2013)

DNA damage induced by nitric oxide during ionizing radiation is enhanced at replication
by: Folkes, L, et al.
Published: (2013)

Thiyl radicals react with nitric oxide to form S-nitrosothiols with rate constants near the diffusion-controlled limit.
by: Madej, E, et al.
Published: (2008)

Cytotoxicity, dose-enhancement and radiosensitization and Radiosensitization of glioblastoma cells with Rare Earth nanoparticles
by: Lu, V, et al.
Published: (2019)

Radiation dose to radiosensitive organs in PET/CT myocardial perfusion examination using versatile optical fibre
by: Salasiah, M., et al.
Published: (2013)

Oxidative activation of indole-3-acetic acids to cytotoxic species- a potential new role for plant auxins in cancer therapy.
by: Folkes, L, et al.
Published: (2001)

Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential for targeted cancer therapy.
by: Rossiter, S, et al.
Published: (2002)

Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin.
by: Bauerschmidt, C, et al.
Published: (2010)

Combining oncolytic adenovirus with radiation – a paradigm for the future of radiosensitization
by: O'Cathail, S, et al.
Published: (2017)

Influence of plasma glutathione levels on radiation mucositis.
by: Wardman, P, et al.
Published: (2001)

Oxidative metabolism of combretastatin A-1 produces quinone intermediates with the potential to bind to nucleophiles and to enhance oxidative stress via free radicals.
by: Folkes, L, et al.
Published: (2007)

Enhancing the efficacy of photodynamic cancer therapy by radicals from plant auxin (indole-3-acetic acid).
by: Folkes, L, et al.
Published: (2003)

The development of doped radiosensitive glass
by: Bradley, D. A., et al.
Published: (2007)

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia
by: Ashton, T, et al.
Published: (2016)

Low-dose nitric oxide as targeted anti-biofilm adjunctive therapy to treat chronic Pseudomonas aeruginosa infection in cystic fibrosis
by: Howlin, RP, et al.
Published: (2017)

Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells.
by: Bauerschmidt, C, et al.
Published: (2011)

Radiation chemistry comes before radiation biology.
by: O'Neill, P, et al.
Published: (2009)

In situ biological dose mapping estimates the radiation burden delivered to 'spared' tissue between synchrotron X-ray microbeam radiotherapy tracks.
by: Rothkamm, K, et al.
Published: (2012)

Radiosensitation in vivo by histone deacetylase inhibition with no increase in early normal tissue radiation toxicity
by: Groselj, B, et al.
Published: (2017)

Exhaled nitric oxide and inhaled corticosteroid dose reduction in asthma: a cohort study.
by: Wilson, E, et al.
Published: (2014)

Transition metal compounds as cancer radiosensitizers
by: Gill, M, et al.
Published: (2018)

Reactivity toward thiols and cytotoxicity of 3-methylene-2-oxindoles, cytotoxins from indole-3-acetic acids, on activation by peroxidases.
by: Folkes, L, et al.
Published: (2002)

The clinical implications of gemcitabine radiosensitization.
by: Doyle, T, et al.
Published: (2001)

The role of nitrite and nitric oxide under low oxygen conditions in plants
by: Gupta, K, et al.
Published: (2019)

Measurement of nitric oxide production by the lesioned rat retina with a sensitive nitric oxide electrode.
by: Groppe, M, et al.
Published: (2003)

Hemoglobin and nitric oxide dependent vasodilation
by: Madsen, P, et al.
Published: (2005)

Nitric oxide production.
by: Young, J, et al.
Published: (1997)

Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study.
by: Ng, Q, et al.
Published: (2007)

Nitric oxide and vascular disease
by: Shirodaria, C, et al.
Published: (2007)

TOPK as a novel determinant of radiosensitivity
by: Pirovano, GM
Published: (2016)

Radiation and litigation : analyses of the ALARA principle and low dose radiation in the courts, and the future of radiation in court cases
by: Esparza, Enrique
Published: (2008)

Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide
by: Amal, Haitham, et al.
Published: (2020)

Kinetics of reaction of nitrogen dioxide with dihydrorhodamine and the reaction of the dihydrorhodamine radical with oxygen: implications for quantifying peroxynitrite formation in cells.
by: Folkes, L, et al.
Published: (2009)

Dose- and time-dependent changes in gene expression in human glioma cells after low radiation doses.
by: Short, S, et al.
Published: (2007)

ROTATIONAL SPECTRA OF RARE-GAS NITRIC-OXIDE VANDERWAALS MOLECULES .2. THE STRUCTURE AND SPECTRUM OF ARGON NITRIC-OXIDE
by: Mills, P, et al.
Published: (1986)

The toxicology of nitric oxide In vitro
by: Gal, Aharon
Published: (2007)