Primary prevention of cardiovascular events in diabetes: is there a role for aspirin?

The POPADAD (Prevention Of Progression of Arterial Disease And Diabetes) study did not show a benefit for low-dose aspirin therapy or administration of antioxidants for the primary prevention of cardiovascular disease events in individuals with diabetes and asymptomatic peripheral arterial disease....

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Price, H, Holman, R
Μορφή: Journal article
Γλώσσα:English
Έκδοση: 2009
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author Price, H
Holman, R
author_facet Price, H
Holman, R
author_sort Price, H
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description The POPADAD (Prevention Of Progression of Arterial Disease And Diabetes) study did not show a benefit for low-dose aspirin therapy or administration of antioxidants for the primary prevention of cardiovascular disease events in individuals with diabetes and asymptomatic peripheral arterial disease. Although low-dose aspirin continues to be recommended in international guidelines, no convincing trial-based evidence exists that supports its routine use for primary prevention of cardiovascular disease in people with diabetes. This paradox is unhelpful and the guidelines should be relaxed until definitive evidence becomes available.
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spelling oxford-uuid:c41237dc-0abe-4ddb-b926-f9bd4c120df32022-03-27T06:20:52ZPrimary prevention of cardiovascular events in diabetes: is there a role for aspirin?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c41237dc-0abe-4ddb-b926-f9bd4c120df3EnglishSymplectic Elements at Oxford2009Price, HHolman, RThe POPADAD (Prevention Of Progression of Arterial Disease And Diabetes) study did not show a benefit for low-dose aspirin therapy or administration of antioxidants for the primary prevention of cardiovascular disease events in individuals with diabetes and asymptomatic peripheral arterial disease. Although low-dose aspirin continues to be recommended in international guidelines, no convincing trial-based evidence exists that supports its routine use for primary prevention of cardiovascular disease in people with diabetes. This paradox is unhelpful and the guidelines should be relaxed until definitive evidence becomes available.
spellingShingle Price, H
Holman, R
Primary prevention of cardiovascular events in diabetes: is there a role for aspirin?
title Primary prevention of cardiovascular events in diabetes: is there a role for aspirin?
title_full Primary prevention of cardiovascular events in diabetes: is there a role for aspirin?
title_fullStr Primary prevention of cardiovascular events in diabetes: is there a role for aspirin?
title_full_unstemmed Primary prevention of cardiovascular events in diabetes: is there a role for aspirin?
title_short Primary prevention of cardiovascular events in diabetes: is there a role for aspirin?
title_sort primary prevention of cardiovascular events in diabetes is there a role for aspirin
work_keys_str_mv AT priceh primarypreventionofcardiovasculareventsindiabetesistherearoleforaspirin
AT holmanr primarypreventionofcardiovasculareventsindiabetesistherearoleforaspirin