T-cell depletion with Campath-1H "in the bag" for matched related allogeneic peripheral blood stem cell transplantation is associated with reduced graft-versus-host disease, rapid immune constitution and improved survival.

T-cell depletion with Campath-1H "in the bag" for matched related allogeneic peripheral blood stem cell transplantation is associated with reduced graft-versus-host disease, rapid immune constitution and improved survival.

We studied the outcome of 24 peripheral blood stem cell (PBSC) graft recipients, who were T-cell depleted (TCD) with either 20 mg (n = 14) or 10 mg (n = 10) Campath-1H in vitro, in comparison with a retrospective cohort of 23 unmanipulated (UM) PBSC recipients. While the neutrophil engraftment was s...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Chakrabarti, S, MacDonald, D, Hale, G, Holder, K, Turner, V, Czarnecka, H, Thompson, J, Fegan, C, Waldmann, H, Milligan, D
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2003

Ижил төстэй зүйлс

T cell depletion with CAMPATH-1 in allogeneic bone marrow transplantation.
-н: Hale, G, зэрэг
Хэвлэсэн: (1988)

Alemtuzumab (Campath-1H) in allogeneic stem cell transplantation: where do we go from here?
-н: Chakrabarti, S, зэрэг
Хэвлэсэн: (2004)

Campath 1 H "in the bag" is an effective method of GvHD prevention in allogeneic stem cell transplantation.
-н: Potter, M, зэрэг
Хэвлэсэн: (2000)

COMBINED USE OF CAMPATH-1G IN-VIVO AND IN THE BAG IN ALLOGENEIC BONE-MARROW TRANSPLANTATION
-н: Fibbe, W, зэрэг
Хэвлэсэн: (1993)

T-cell depletion of stem cell grafts with campath-1H "in the bag" followed by cyclosporin immunosuppression remains a cost effective strategy in transplantation
-н: Novitzky, N, зэрэг
Хэвлэсэн: (2004)

Reconstitution of the Epstein-Barr virus-specific cytotoxic T-lymphocyte response following T-cell-depleted myeloablative and nonmyeloablative allogeneic stem cell transplantation.
-н: Chakrabarti, S, зэрэг
Хэвлэсэн: (2003)

Addition of cyclosporin post transplantation decreases GvHD without enhancing the adverse effect of T-cell depletion with CAMPATH-1H "in the bag": The cape town experience
-н: Novitzky, N, зэрэг
Хэвлэсэн: (2003)

CAMPATH-1 antibodies in stem-cell transplantation.
-н: Hale, G, зэрэг
Хэвлэсэн: (2001)

Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies. Results of matched sibling transplants for malignant diseases.
-н: Hale, G, зэрэг
Хэвлэсэн: (1994)

Campath-1 Abs 'in the bag' for hematological malignancies: the Cape Town experience.
-н: Novitzky, N, зэрэг
Хэвлэсэн: (2004)

Impact on T-cell depletion and CD34+ cell recovery using humanised CD52 monoclonal antibody (CAMPATH-1H) in BM and PSBC collections; comparison with CAMPATH-1M and CAMPATH-1G.
-н: Williams, R, зэрэг
Хэвлэсэн: (2000)

T-CELL DEPLETION BY EXPOSURE TO CAMPATH-1G IN-VITRO PREVENTS GRAFT-VERSUS-HOST DISEASE
-н: Jacobs, P, зэрэг
Хэвлэсэн: (1994)

Risks of developing Epstein-Barr virus-related lymphoproliferative disorders after T-cell-depleted marrow transplants. CAMPATH Users.
-н: Hale, G, зэрэг
Хэвлэсэн: (1998)

T cell depletion by exposure to Campath-1G in vitro prevents graft-versus-host disease.
-н: Jacobs, P, зэрэг
Хэвлэсэн: (1994)

Ex vivo T-cell depletion with the monoclonal antibody Campath-1 plus human complement effectively prevents acute graft-versus-host disease in allogeneic bone marrow transplantation.
-н: Heit, W, зэрэг
Хэвлэсэн: (1986)

RESULTS OF T-CELL DEPLETION WITH CAMPATH-1 IN BONE-MARROW TRANSPLANTATION (BMT) FOR CHRONIC GRANULOCYTIC-LEUKEMIA (CGL)
-н: Apperley, J, зэрэг
Хэвлэсэн: (1985)

CAMPATH: from concept to clinic.
-н: Waldmann, H, зэрэг
Хэвлэсэн: (2005)

Peripheral blood dendritic cells express CD52 and are depleted in-vivo by treatment with CAMPATH-1H.
-н: Buggins, A, зэрэг
Хэвлэсэн: (2001)

Use of Ceprate CD34-positive selection system for depletion of T cells in allogeneic transplantation.
-н: Hale, G, зэрэг
Хэвлэсэн: (1997)

Specificity of monoclonal antibody Campath-1.
-н: Hale, G, зэрэг
Хэвлэсэн: (1988)

T-cell depletion of bone marrow grafts with Campath 1 ex vivo prevents graft-versus-host disease without abrogating the antileukaemic effect of transplantation
-н: Novitzky, N, зэрэг
Хэвлэсэн: (1997)

Ex vivo T-cell depletion of bone marrow grafts with campath 1 prevents graft-versus-host disease without abrogating the antileukaemic effect of transplantation.
-н: Novitzky, N, зэрэг
Хэвлэсэн: (1997)

Respiratory virus infections in transplant recipients after reduced-intensity conditioning with Campath-1H: high incidence but low mortality.
-н: Chakrabarti, S, зэрэг
Хэвлэсэн: (2002)

Availability of Campath-1 antibodies for bone marrow transplantation.
-н: Hale, G, зэрэг
Хэвлэсэн: (1995)

CAMPATH-1 monoclonal antibodies in bone marrow transplantation.
-н: Hale, G, зэрэг
Хэвлэсэн: (1994)

Outcome following T-cell depletion of allogeneic peripheral blood progenitor cells for transplantation
-н: Novitzky, N, зэрэг
Хэвлэсэн: (1997)

Allogeneic stem cell transplantation for lymphoproliferative disease using BEAM-Campath conditioning: An effective regime with low procedure-related toxicity.
-н: Cull, G, зэрэг
Хэвлэсэн: (1999)

Ex vivo depletion of T cells from bone marrow grafts with CAMPATH-1 in acute leukemia: graft-versus-host disease and graft-versus-leukemia effect.
-н: Novitzky, N, зэрэг
Хэвлэсэн: (1999)

Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen.
-н: Xia, M, зэрэг
Хэвлэсэн: (1993)

The CAMPATH-1 antigen (CDw52).
-н: Hale, G, зэрэг
Хэвлэсэн: (1990)

High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: potential role of Campath-1H in delaying immune reconstitution.
-н: Chakrabarti, S, зэрэг
Хэвлэсэн: (2002)

CAMPATH-1H in inflammatory arthritis.
-н: Watts, R, зэрэг
Хэвлэсэн: (1993)

Immune reconstitution after allogeneic bone marrow transplantation depleted of T cells.
-н: Davison, G, зэрэг
Хэвлэсэн: (2000)

Immune reconstitution following allogeneic bone marrow transplantation depleted of T-cells.
-н: Davison, G, зэрэг
Хэвлэсэн: (1998)

Immune reconstitution post T-CELL depleted allogeneic bone marrow transplantation
-н: Davison, G, зэрэг
Хэвлэсэн: (1998)

Preliminary experience of allogeneic stem cell transplantation for lymphoproliferative disorders using BEAM-CAMPATH conditioning: an effective regimen with low procedure-related toxicity.
-н: Cull, G, зэрэг
Хэвлэсэн: (2000)

Recent results using CAMPATH-1 antibodies to control GVHD and graft rejection.
-н: Hale, G, зэрэг
Хэвлэсэн: (1996)

ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR LEUKEMIA USING CAMPATH-1 MONOCLONAL-ANTIBODIES AND POSTTRANSPLANT ALLOIMMUNIZATION WITH DONOR LYMPHOCYTES
-н: Naparstek, E, зэрэг
Хэвлэсэн: (1993)

In vivo CAMPATH-1H prevents GvHD following nonmyeloablative stem-cell transplantation.
-н: Kottaridis, P, зэрэг
Хэвлэсэн: (2001)

CAMPATH-IH in multiple sclerosis.
-н: Moreau, T, зэрэг
Хэвлэсэн: (1996)