Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.

A set of macrocycles was generated by solid phase synthesis of linear trimers of 5-aminoacyl-3-aminomethyl-benzoates followed by resin cleavage and solution phase macrocyclization. These scaffolds can serve as useful building blocks for molecular recognition studies, especially where differentially...

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Main Authors: Jain, R, Tsou, L, Hamilton, A
Format: Journal article
Language:English
Published: 2009
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author Jain, R
Tsou, L
Hamilton, A
author_facet Jain, R
Tsou, L
Hamilton, A
author_sort Jain, R
collection OXFORD
description A set of macrocycles was generated by solid phase synthesis of linear trimers of 5-aminoacyl-3-aminomethyl-benzoates followed by resin cleavage and solution phase macrocyclization. These scaffolds can serve as useful building blocks for molecular recognition studies, especially where differentially functionalized molecular platforms spanning large surface areas are required.
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spelling oxford-uuid:c4299747-6403-4177-91fd-a1523d55674a2022-03-27T06:21:34ZCombined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c4299747-6403-4177-91fd-a1523d55674aEnglishSymplectic Elements at Oxford2009Jain, RTsou, LHamilton, AA set of macrocycles was generated by solid phase synthesis of linear trimers of 5-aminoacyl-3-aminomethyl-benzoates followed by resin cleavage and solution phase macrocyclization. These scaffolds can serve as useful building blocks for molecular recognition studies, especially where differentially functionalized molecular platforms spanning large surface areas are required.
spellingShingle Jain, R
Tsou, L
Hamilton, A
Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.
title Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.
title_full Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.
title_fullStr Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.
title_full_unstemmed Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.
title_short Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.
title_sort combined solid solution phase synthesis of large surface area scaffolds derived from aminomethyl benzoates
work_keys_str_mv AT jainr combinedsolidsolutionphasesynthesisoflargesurfaceareascaffoldsderivedfromaminomethylbenzoates
AT tsoul combinedsolidsolutionphasesynthesisoflargesurfaceareascaffoldsderivedfromaminomethylbenzoates
AT hamiltona combinedsolidsolutionphasesynthesisoflargesurfaceareascaffoldsderivedfromaminomethylbenzoates