Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.
A set of macrocycles was generated by solid phase synthesis of linear trimers of 5-aminoacyl-3-aminomethyl-benzoates followed by resin cleavage and solution phase macrocyclization. These scaffolds can serve as useful building blocks for molecular recognition studies, especially where differentially...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2009
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_version_ | 1797093402268925952 |
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author | Jain, R Tsou, L Hamilton, A |
author_facet | Jain, R Tsou, L Hamilton, A |
author_sort | Jain, R |
collection | OXFORD |
description | A set of macrocycles was generated by solid phase synthesis of linear trimers of 5-aminoacyl-3-aminomethyl-benzoates followed by resin cleavage and solution phase macrocyclization. These scaffolds can serve as useful building blocks for molecular recognition studies, especially where differentially functionalized molecular platforms spanning large surface areas are required. |
first_indexed | 2024-03-07T03:59:50Z |
format | Journal article |
id | oxford-uuid:c4299747-6403-4177-91fd-a1523d55674a |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T03:59:50Z |
publishDate | 2009 |
record_format | dspace |
spelling | oxford-uuid:c4299747-6403-4177-91fd-a1523d55674a2022-03-27T06:21:34ZCombined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c4299747-6403-4177-91fd-a1523d55674aEnglishSymplectic Elements at Oxford2009Jain, RTsou, LHamilton, AA set of macrocycles was generated by solid phase synthesis of linear trimers of 5-aminoacyl-3-aminomethyl-benzoates followed by resin cleavage and solution phase macrocyclization. These scaffolds can serve as useful building blocks for molecular recognition studies, especially where differentially functionalized molecular platforms spanning large surface areas are required. |
spellingShingle | Jain, R Tsou, L Hamilton, A Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates. |
title | Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates. |
title_full | Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates. |
title_fullStr | Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates. |
title_full_unstemmed | Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates. |
title_short | Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates. |
title_sort | combined solid solution phase synthesis of large surface area scaffolds derived from aminomethyl benzoates |
work_keys_str_mv | AT jainr combinedsolidsolutionphasesynthesisoflargesurfaceareascaffoldsderivedfromaminomethylbenzoates AT tsoul combinedsolidsolutionphasesynthesisoflargesurfaceareascaffoldsderivedfromaminomethylbenzoates AT hamiltona combinedsolidsolutionphasesynthesisoflargesurfaceareascaffoldsderivedfromaminomethylbenzoates |