Combined solid/solution phase synthesis of large surface area scaffolds derived from aminomethyl-benzoates.

A set of macrocycles was generated by solid phase synthesis of linear trimers of 5-aminoacyl-3-aminomethyl-benzoates followed by resin cleavage and solution phase macrocyclization. These scaffolds can serve as useful building blocks for molecular recognition studies, especially where differentially...

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Bibliographic Details
Main Authors: Jain, R, Tsou, L, Hamilton, A
Format: Journal article
Language:English
Published: 2009