Failed gene conversion leads to extensive end processing and chromosomal rearrangements in fission yeast.

Failed gene conversion leads to extensive end processing and chromosomal rearrangements in fission yeast.

Loss of heterozygosity (LOH), a causal event in cancer and human genetic diseases, frequently encompasses multiple genetic loci and whole chromosome arms. However, the mechanisms by which such extensive LOH arises, and how it is suppressed in normal cells is poorly understood. We have developed a ge...

Detaylı Bibliyografya
Asıl Yazarlar:	Tinline-Purvis, H, Savory, A, Cullen, J, Davé, A, Moss, J, Bridge, W, Marguerat, S, Bähler, J, Ragoussis, J, Mott, R, Walker, C, Humphrey, T
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2009

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