Control of Listeria monocytogenes virulence by 5'-untranslated RNA.
The Gram-positive bacterium Listeria monocytogenes uses a wide range of virulence factors for its pathogenesis. Expression of five of these factors has previously been shown to be subjected to post-transcriptional regulation as a result of their long 5'-untranslated region (5'-UTR). We hav...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2006
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| _version_ | 1797093434674118656 |
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| author | Loh, E Gripenland, J Johansson, J |
| author_facet | Loh, E Gripenland, J Johansson, J |
| author_sort | Loh, E |
| collection | OXFORD |
| description | The Gram-positive bacterium Listeria monocytogenes uses a wide range of virulence factors for its pathogenesis. Expression of five of these factors has previously been shown to be subjected to post-transcriptional regulation as a result of their long 5'-untranslated region (5'-UTR). We have investigated the presence of 5'-UTRs among the other known virulence genes and genes that encode putatively virulence-associated surface proteins. Our results strongly suggest that L. monocytogenes controls many of its virulence genes by a mechanism that involves the 5'-UTR. These findings further emphasize the importance of post-transcriptional control for L. monocytogenes virulence. |
| first_indexed | 2024-03-07T04:00:19Z |
| format | Journal article |
| id | oxford-uuid:c45ba5f4-0ceb-4526-ab4f-60f66213e1e8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:00:19Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:c45ba5f4-0ceb-4526-ab4f-60f66213e1e82022-03-27T06:22:47ZControl of Listeria monocytogenes virulence by 5'-untranslated RNA.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c45ba5f4-0ceb-4526-ab4f-60f66213e1e8EnglishSymplectic Elements at Oxford2006Loh, EGripenland, JJohansson, JThe Gram-positive bacterium Listeria monocytogenes uses a wide range of virulence factors for its pathogenesis. Expression of five of these factors has previously been shown to be subjected to post-transcriptional regulation as a result of their long 5'-untranslated region (5'-UTR). We have investigated the presence of 5'-UTRs among the other known virulence genes and genes that encode putatively virulence-associated surface proteins. Our results strongly suggest that L. monocytogenes controls many of its virulence genes by a mechanism that involves the 5'-UTR. These findings further emphasize the importance of post-transcriptional control for L. monocytogenes virulence. |
| spellingShingle | Loh, E Gripenland, J Johansson, J Control of Listeria monocytogenes virulence by 5'-untranslated RNA. |
| title | Control of Listeria monocytogenes virulence by 5'-untranslated RNA. |
| title_full | Control of Listeria monocytogenes virulence by 5'-untranslated RNA. |
| title_fullStr | Control of Listeria monocytogenes virulence by 5'-untranslated RNA. |
| title_full_unstemmed | Control of Listeria monocytogenes virulence by 5'-untranslated RNA. |
| title_short | Control of Listeria monocytogenes virulence by 5'-untranslated RNA. |
| title_sort | control of listeria monocytogenes virulence by 5 untranslated rna |
| work_keys_str_mv | AT lohe controloflisteriamonocytogenesvirulenceby5untranslatedrna AT gripenlandj controloflisteriamonocytogenesvirulenceby5untranslatedrna AT johanssonj controloflisteriamonocytogenesvirulenceby5untranslatedrna |