Effects of NXY-059 in experimental stroke: an individual animal meta-analysis.

BACKGROUND AND PURPOSE: Disodium 2,4-disulphophenyl-N-tert-butylnitrone (NXY-059) was neuroprotective in experimental stroke models but ineffective in a large clinical trial. This first-ever individual animal meta-analysis was used to assess the preclinical studies. EXPERIMENTAL APPROACH: Studies w...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Bath, P, Gray, L, Bath, A, Buchan, A, Miyata, T, Green, A
Format: Journal article
Sprache:English
Veröffentlicht: 2009