SYNTHESIS OF 1,5-DIDEOXY-3-O-(ALPHA-D-MANNOPYRANOSYL)-1,5-IMINO-D-MANNITOL AND 1,5-DIDEOXY-3-O-(ALPHA-D-GLUCOPYRANOSYL)-1,5-IMINO-D-MANNITOL - POWERFUL INHIBITORS OF ENDOMANNOSIDASE
The synthesis and conformations of 3-O-methylDMJ, 3-O-(α-D-glucopyranosyl)-DMJ (Glcα1,3DMJ), and 3-O-(α-D-mannopyranosyl)-DMJ (Manα1,3DMJ) are described. Manα1,3DMJ and Glcα1,3DMJ are shown to be very powerful inhibitors of an endomannosidase. The potential use of these compounds in both probing the...
Váldodahkkit: | , , , , , , |
---|---|
Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
1993
|