Stepwise mutation likelihood computation by sequential importance sampling in subdivided population models.

An importance sampling algorithm for computing the likelihood of a sample of genes at loci under a stepwise mutation model in a subdivided population is developed. This allows maximum likelihood estimation of migration rates between subpopulations. The time to the most recent common ancestor of the...

詳細記述

書誌詳細
主要な著者: De Iorio, M, Griffiths, R, Leblois, R, Rousset, F
フォーマット: Journal article
言語:English
出版事項: 2005
その他の書誌記述
要約:An importance sampling algorithm for computing the likelihood of a sample of genes at loci under a stepwise mutation model in a subdivided population is developed. This allows maximum likelihood estimation of migration rates between subpopulations. The time to the most recent common ancestor of the sample can also be computed. The technique is illustrated by an analysis of a data set of Australian red fox populations.