Stepwise mutation likelihood computation by sequential importance sampling in subdivided population models.

An importance sampling algorithm for computing the likelihood of a sample of genes at loci under a stepwise mutation model in a subdivided population is developed. This allows maximum likelihood estimation of migration rates between subpopulations. The time to the most recent common ancestor of the...

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Main Authors: De Iorio, M, Griffiths, R, Leblois, R, Rousset, F
Format: Journal article
Jezik:English
Izdano: 2005
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author De Iorio, M
Griffiths, R
Leblois, R
Rousset, F
author_facet De Iorio, M
Griffiths, R
Leblois, R
Rousset, F
author_sort De Iorio, M
collection OXFORD
description An importance sampling algorithm for computing the likelihood of a sample of genes at loci under a stepwise mutation model in a subdivided population is developed. This allows maximum likelihood estimation of migration rates between subpopulations. The time to the most recent common ancestor of the sample can also be computed. The technique is illustrated by an analysis of a data set of Australian red fox populations.
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institution University of Oxford
language English
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spelling oxford-uuid:c48b19a6-bd5e-436e-b308-db5bd315d3b72022-03-27T06:24:05ZStepwise mutation likelihood computation by sequential importance sampling in subdivided population models.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c48b19a6-bd5e-436e-b308-db5bd315d3b7EnglishSymplectic Elements at Oxford2005De Iorio, MGriffiths, RLeblois, RRousset, FAn importance sampling algorithm for computing the likelihood of a sample of genes at loci under a stepwise mutation model in a subdivided population is developed. This allows maximum likelihood estimation of migration rates between subpopulations. The time to the most recent common ancestor of the sample can also be computed. The technique is illustrated by an analysis of a data set of Australian red fox populations.
spellingShingle De Iorio, M
Griffiths, R
Leblois, R
Rousset, F
Stepwise mutation likelihood computation by sequential importance sampling in subdivided population models.
title Stepwise mutation likelihood computation by sequential importance sampling in subdivided population models.
title_full Stepwise mutation likelihood computation by sequential importance sampling in subdivided population models.
title_fullStr Stepwise mutation likelihood computation by sequential importance sampling in subdivided population models.
title_full_unstemmed Stepwise mutation likelihood computation by sequential importance sampling in subdivided population models.
title_short Stepwise mutation likelihood computation by sequential importance sampling in subdivided population models.
title_sort stepwise mutation likelihood computation by sequential importance sampling in subdivided population models
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AT griffithsr stepwisemutationlikelihoodcomputationbysequentialimportancesamplinginsubdividedpopulationmodels
AT lebloisr stepwisemutationlikelihoodcomputationbysequentialimportancesamplinginsubdividedpopulationmodels
AT roussetf stepwisemutationlikelihoodcomputationbysequentialimportancesamplinginsubdividedpopulationmodels