Glimepiride block of cloned beta-cell, cardiac and smooth muscle K(ATP) channels.
1. We examined the effect of the sulphonylurea glimepiride on three types of recombinant ATP-sensitive potassium (K(ATP)) channels. 2. K(ATP) channels share a common pore-forming subunit, Kir6.2, which associates with different sulphonylurea receptor isoforms (SUR1 in beta-cells, SUR2A in heart and...
Main Authors: | Song, D, Ashcroft, F |
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Format: | Journal article |
Language: | English |
Published: |
2001
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