mTOR: dissecting regulation and mechanism of action to understand human disease.
mTOR (mammalian target of rapamycin) is a highly conserved serine/threonine protein kinase that has roles in cell metabolism, cell growth and cell survival. Although it has been known for some years that mTOR acts as a hub for inputs from growth factors (in particular insulin and insulin-like growth...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2009
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