An update on hepatitis C virus.
Chronic hepatitis caused by hepatitis C virus infection is one of the leading causes of liver cirrhosis and hepatocellular carcinoma globally. Over the last few years, there have been significant advances in our understanding of the immunopathogenesis of this infection, as well as revolutionary deve...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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Royal College of Physicians
2015
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| _version_ | 1826295473513693184 |
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| author | Klenerman, P Fitzmaurice, K |
| author_facet | Klenerman, P Fitzmaurice, K |
| author_sort | Klenerman, P |
| collection | OXFORD |
| description | Chronic hepatitis caused by hepatitis C virus infection is one of the leading causes of liver cirrhosis and hepatocellular carcinoma globally. Over the last few years, there have been significant advances in our understanding of the immunopathogenesis of this infection, as well as revolutionary developments in the therapeutic armamentarium. The introduction of a number of new oral antiviral agents is already delivering major benefits to patients as they are generally well tolerated and are associated with excellent response rates in the majority. Nonetheless, a number of clinical scenarios remain challenging and research is ongoing in these areas. In this update, we review developments in both basic as well as translational research in the field. |
| first_indexed | 2024-03-07T04:01:35Z |
| format | Journal article |
| id | oxford-uuid:c4c07269-826c-4cfa-8928-b3fe5f91e729 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:01:35Z |
| publishDate | 2015 |
| publisher | Royal College of Physicians |
| record_format | dspace |
| spelling | oxford-uuid:c4c07269-826c-4cfa-8928-b3fe5f91e7292022-03-27T06:25:53ZAn update on hepatitis C virus.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c4c07269-826c-4cfa-8928-b3fe5f91e729EnglishSymplectic Elements at OxfordRoyal College of Physicians2015Klenerman, PFitzmaurice, KChronic hepatitis caused by hepatitis C virus infection is one of the leading causes of liver cirrhosis and hepatocellular carcinoma globally. Over the last few years, there have been significant advances in our understanding of the immunopathogenesis of this infection, as well as revolutionary developments in the therapeutic armamentarium. The introduction of a number of new oral antiviral agents is already delivering major benefits to patients as they are generally well tolerated and are associated with excellent response rates in the majority. Nonetheless, a number of clinical scenarios remain challenging and research is ongoing in these areas. In this update, we review developments in both basic as well as translational research in the field. |
| spellingShingle | Klenerman, P Fitzmaurice, K An update on hepatitis C virus. |
| title | An update on hepatitis C virus. |
| title_full | An update on hepatitis C virus. |
| title_fullStr | An update on hepatitis C virus. |
| title_full_unstemmed | An update on hepatitis C virus. |
| title_short | An update on hepatitis C virus. |
| title_sort | update on hepatitis c virus |
| work_keys_str_mv | AT klenermanp anupdateonhepatitiscvirus AT fitzmauricek anupdateonhepatitiscvirus AT klenermanp updateonhepatitiscvirus AT fitzmauricek updateonhepatitiscvirus |