Intestinal inflammation abrogates the tolerogenic properties of MLN CD103+ dendritic cells.

Intestinal inflammation abrogates the tolerogenic properties of MLN CD103+ dendritic cells.

Intestinal CD103(+) DC promote the differentiation of Foxp3(+) Treg from naïve CD4(+) T cells through mechanisms involving TGF-beta and the dietary metabolite, retinoic acid (RA). In this study, we have analysed whether the specialised features of CD103(+) DC are conserved in colitis. Our results sh...

書目詳細資料
Main Authors:	Laffont, S, Siddiqui, K, Powrie, F
格式:	Journal article
語言:	English
出版:	2010

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