On the origin of oscillopsia during pedunculopontine stimulation.
We report a case of induced oscillopsia caused by deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN). Recent reports have described involuntary oscillopsia during DBS of the PPN that patients have described as trembling vision. Here we substantiate this observation using infra-red ey...
| Những tác giả chính: | , , , , |
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| Định dạng: | Journal article |
| Ngôn ngữ: | English |
| Được phát hành: |
2012
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| _version_ | 1826295491980165120 |
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| author | Jenkinson, N Brittain, J Hicks, S Kennard, C Aziz, T |
| author_facet | Jenkinson, N Brittain, J Hicks, S Kennard, C Aziz, T |
| author_sort | Jenkinson, N |
| collection | OXFORD |
| description | We report a case of induced oscillopsia caused by deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN). Recent reports have described involuntary oscillopsia during DBS of the PPN that patients have described as trembling vision. Here we substantiate this observation using infra-red eye tracking. It has been suggested that this phenomenon might be used as an indicator of accurate targeting of the PPN with DBS. Our observations suggest that this phenomenon may not be related to a constricted anatomical structure and therefore such practise may be unwise. Scrutiny has led us to believe that the oscillopsia in our patient is not caused by direct stimulation of the oculomotor nerve as suggested in a previous report, but by stimulation of fibres in the uncinate fasciculus of the cerebellum and the superior cerebellar peduncle, which in turn stimulate the saccadic pre-motor neurones in the brainstem. |
| first_indexed | 2024-03-07T04:01:51Z |
| format | Journal article |
| id | oxford-uuid:c4d64d73-9f39-4d31-b0a0-2b0c67fc1f13 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:01:51Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | oxford-uuid:c4d64d73-9f39-4d31-b0a0-2b0c67fc1f132022-03-27T06:26:36ZOn the origin of oscillopsia during pedunculopontine stimulation.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c4d64d73-9f39-4d31-b0a0-2b0c67fc1f13EnglishSymplectic Elements at Oxford2012Jenkinson, NBrittain, JHicks, SKennard, CAziz, TWe report a case of induced oscillopsia caused by deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN). Recent reports have described involuntary oscillopsia during DBS of the PPN that patients have described as trembling vision. Here we substantiate this observation using infra-red eye tracking. It has been suggested that this phenomenon might be used as an indicator of accurate targeting of the PPN with DBS. Our observations suggest that this phenomenon may not be related to a constricted anatomical structure and therefore such practise may be unwise. Scrutiny has led us to believe that the oscillopsia in our patient is not caused by direct stimulation of the oculomotor nerve as suggested in a previous report, but by stimulation of fibres in the uncinate fasciculus of the cerebellum and the superior cerebellar peduncle, which in turn stimulate the saccadic pre-motor neurones in the brainstem. |
| spellingShingle | Jenkinson, N Brittain, J Hicks, S Kennard, C Aziz, T On the origin of oscillopsia during pedunculopontine stimulation. |
| title | On the origin of oscillopsia during pedunculopontine stimulation. |
| title_full | On the origin of oscillopsia during pedunculopontine stimulation. |
| title_fullStr | On the origin of oscillopsia during pedunculopontine stimulation. |
| title_full_unstemmed | On the origin of oscillopsia during pedunculopontine stimulation. |
| title_short | On the origin of oscillopsia during pedunculopontine stimulation. |
| title_sort | on the origin of oscillopsia during pedunculopontine stimulation |
| work_keys_str_mv | AT jenkinsonn ontheoriginofoscillopsiaduringpedunculopontinestimulation AT brittainj ontheoriginofoscillopsiaduringpedunculopontinestimulation AT hickss ontheoriginofoscillopsiaduringpedunculopontinestimulation AT kennardc ontheoriginofoscillopsiaduringpedunculopontinestimulation AT azizt ontheoriginofoscillopsiaduringpedunculopontinestimulation |