The kinetic-segregation model: TCR triggering and beyond
How the T cell receptor engages antigen is known, but not how that 'triggers' intracellular signaling. The first direct support for a mechanism based on the spatial reorganization of signaling proteins, proposed 10 years ago and referred to as the 'kinetic-segregation' model, is...
Main Authors: | Davis, S, Van Der Merwe, P |
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Format: | Journal article |
Language: | English |
Published: |
2006
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