The kinetic-segregation model: TCR triggering and beyond

The kinetic-segregation model: TCR triggering and beyond

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How the T cell receptor engages antigen is known, but not how that 'triggers' intracellular signaling. The first direct support for a mechanism based on the spatial reorganization of signaling proteins, proposed 10 years ago and referred to as the 'kinetic-segregation' model, is...

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Detalhes bibliográficos
Principais autores:	Davis, S, Van Der Merwe, P
Formato:	Journal article
Idioma:	English
Publicado em:	2006

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