The kinetic-segregation model: TCR triggering and beyond

How the T cell receptor engages antigen is known, but not how that 'triggers' intracellular signaling. The first direct support for a mechanism based on the spatial reorganization of signaling proteins, proposed 10 years ago and referred to as the 'kinetic-segregation' model, is...

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Váldodahkkit: Davis, S, Van Der Merwe, P
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2006