Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment.
A 24-year-old man with severe Plasmodium falciparum malaria died after 77 h of treatment with full parenteral doses of quinine. His peripheral parasitemia at death exceeded the level on admission. Plasma concentrations of quinine were abnormally low throughout. This case emphasizes the importance of...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1990
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| _version_ | 1797093595188035584 |
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| author | Looareesuwan, S Charoenpan, P Ho, M White, N Karbwang, J Bunnag, D Harinasuta, T |
| author_facet | Looareesuwan, S Charoenpan, P Ho, M White, N Karbwang, J Bunnag, D Harinasuta, T |
| author_sort | Looareesuwan, S |
| collection | OXFORD |
| description | A 24-year-old man with severe Plasmodium falciparum malaria died after 77 h of treatment with full parenteral doses of quinine. His peripheral parasitemia at death exceeded the level on admission. Plasma concentrations of quinine were abnormally low throughout. This case emphasizes the importance of pharmacokinetic factors in determining the therapeutic response in severe P. falciparum malaria. |
| first_indexed | 2024-03-07T04:02:47Z |
| format | Journal article |
| id | oxford-uuid:c527f250-92e1-4cb2-97ba-de4c342f215c |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T04:02:47Z |
| publishDate | 1990 |
| record_format | dspace |
| spelling | oxford-uuid:c527f250-92e1-4cb2-97ba-de4c342f215c2022-03-27T06:28:47ZFatal Plasmodium falciparum malaria after an inadequate response to quinine treatment.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:c527f250-92e1-4cb2-97ba-de4c342f215cEnglishSymplectic Elements at Oxford1990Looareesuwan, SCharoenpan, PHo, MWhite, NKarbwang, JBunnag, DHarinasuta, TA 24-year-old man with severe Plasmodium falciparum malaria died after 77 h of treatment with full parenteral doses of quinine. His peripheral parasitemia at death exceeded the level on admission. Plasma concentrations of quinine were abnormally low throughout. This case emphasizes the importance of pharmacokinetic factors in determining the therapeutic response in severe P. falciparum malaria. |
| spellingShingle | Looareesuwan, S Charoenpan, P Ho, M White, N Karbwang, J Bunnag, D Harinasuta, T Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment. |
| title | Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment. |
| title_full | Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment. |
| title_fullStr | Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment. |
| title_full_unstemmed | Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment. |
| title_short | Fatal Plasmodium falciparum malaria after an inadequate response to quinine treatment. |
| title_sort | fatal plasmodium falciparum malaria after an inadequate response to quinine treatment |
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