Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies
The human immunoglobulin heavy-chain (IGH) locus is exceptionally polymorphic, with high levels of allelic and structural variation. Thus, germline IGH genotypes are personal, which may influence responses to infection and vaccination. For an improved understanding of inter-individual differences in...
Main Authors: | Pushparaj, P, Nicoletto, A, Sheward, DJ, Das, H, Castro Dopico, X, Perez Vidakovics, L, Hanke, L, Chernyshev, M, Narang, S, Kim, S, Fischbach, J, Ekström, S, McInerney, G, Hällberg, BM, Murrell, B, Corcoran, M, Karlsson Hedestam, GB |
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Format: | Journal article |
Language: | English |
Published: |
Cell Press
2022
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