Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies

The human immunoglobulin heavy-chain (IGH) locus is exceptionally polymorphic, with high levels of allelic and structural variation. Thus, germline IGH genotypes are personal, which may influence responses to infection and vaccination. For an improved understanding of inter-individual differences in...

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Những tác giả chính: Pushparaj, P, Nicoletto, A, Sheward, DJ, Das, H, Castro Dopico, X, Perez Vidakovics, L, Hanke, L, Chernyshev, M, Narang, S, Kim, S, Fischbach, J, Ekström, S, McInerney, G, Hällberg, BM, Murrell, B, Corcoran, M, Karlsson Hedestam, GB
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Cell Press 2022