Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP.

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP.

Rap1 is a small, Ras-like GTPase that was first identified as a protein that could suppress the oncogenic transformation of cells by Ras. Rap1 is activated by several extracellular stimuli and may be involved in cellular processes such as cell proliferation, cell differentiation, T-cell anergy and p...

Podrobná bibliografie
Hlavní autoři:	de Rooij, J, Zwartkruis, F, Verheijen, M, Cool, R, Nijman, S, Wittinghofer, A, Bos, J
Médium:	Journal article
Jazyk:	English
Vydáno:	1998

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