Tracking the dynamic interplay between bacterial and host factors during pathogen-induced vacuole rupture in real time.

Escape into the host cell cytosol following invasion of mammalian cells is a common strategy used by invasive pathogens. This requires membrane rupture of the vesicular or vacuolar compartment formed around the bacteria after uptake into the host cell. The mechanism of pathogen-induced disassembly o...

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Bibliographic Details
Main Authors: Ray, K, Bobard, A, Danckaert, A, Paz-Haftel, I, Clair, C, Ehsani, S, Tang, C, Sansonetti, P, Tran, G, Enninga, J
Format: Journal article
Language:English
Published: 2010