TPC2-mediated Ca2+ signaling is required for the establishment of synchronized activity in developing zebrafish primary motor neurons

During the development of the early spinal circuitry in zebrafish, spontaneous Ca2+ transients in the primary motor neurons (PMNs) are reported to transform from being slow and uncorrelated, to being rapid, synchronized and patterned. In this study, we demonstrated that in intact zebrafish, Ca2+ rel...

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Bibliographic Details
Main Authors: Kelu, JJ, Webb, SE, Galione, A, Miller, AL
Format: Journal article
Language:English
Published: Elsevier 2018