The thiopurine methyltransferase TPMT *1/*3A genotype is associated with a better treatment outcome in the UK ALL97 trial for childhood acute lymphoblastic leukaemia; TPMT heterozygosity is not associated with secondary cancers

Eitemau Tebyg

• Detection of Thiopurine S-Methyltransferase (TPMT) Polymorphisms TPMT*3A, TPMT*3B and TPMT*3C in Children with Acute Lymphoblastic Leukemia
  gan: Nawar S. Mohammed, et al.
  Cyhoeddwyd: (2018-12-01)
• Thiopurine methyltransferase genotype-phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia.
  gan: Lennard, L, et al.
  Cyhoeddwyd: (2013)
• Common Polymorphism’s Analysis of Thiopurine S-Methyltransferase (TPMT) in Iranian Population
  gan: Mehdi Azad, et al.
  Cyhoeddwyd: (2009-01-01)
• In Vitro Protein Stability of Two Naturally Occurring Thiopurine S‑Methyltransferase Variants: Biophysical Characterization of TPMT*6 and TPMT*8
  gan: Patricia Wennerstrand, et al.
  Cyhoeddwyd: (2017-08-01)
• Thiopurine methyltransferase (TPMT), nudix hydrolase 15 (NUDT-15) and methylene tetrahydrofolate reductase (MTHFR)polymorphisms in children with acute lymphoblastic leukaemia
  gan: Srikanth Marda, et al.
  Cyhoeddwyd: (2022-01-01)