Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin.

OBJECTIVE: A major site of action for the atheroprotective drug nicotinic acid (NA) is adipose tissue, via the G-protein-coupled receptor, GPR109A. Since, adipose tissue is an active secretory organ that contributes both positively and negatively to systemic inflammatory processes associated with c...

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Bibliografski detalji
Glavni autori: Digby, J, McNeill, E, Dyar, O, Lam, V, Greaves, D, Choudhury, R
Format: Journal article
Jezik:English
Izdano: 2010

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