A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.
To identify new risk variants for cutaneous basal cell carcinoma, we performed a genome-wide association study of 16 million SNPs identified through whole-genome sequencing of 457 Icelanders. We imputed genotypes for 41,675 Illumina SNP chip-typed Icelanders and their relatives. In the discovery pha...
Những tác giả chính: | Stacey, SN, Sulem, P, Jonasdottir, A, Masson, G, Gudmundsson, J, Gudbjartsson, D, Magnusson, O, Gudjonsson, SA, Sigurgeirsson, B, Thorisdottir, K, Ragnarsson, R, Benediktsdottir, K, Nexø, B, Tjønneland, A, Overvad, K, Rudnai, P, Gurzau, E, Koppova, K, Hemminki, K, Corredera, C, Fuentelsaz, V, Grasa, P, Navarrete, S, Fuertes, F, García-Prats, MD |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2011
|
Những quyển sách tương tự
-
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
Bằng: Stacey, SN, et al.
Được phát hành: (2011) -
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.
Bằng: Rafnar, T, et al.
Được phát hành: (2009) -
A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer
Bằng: Gudmundsson, J, et al.
Được phát hành: (2012) -
Parental origin of sequence variants associated with complex diseases.
Bằng: Kong, A, et al.
Được phát hành: (2009) -
Parental origin of sequence variants associated with complex diseases
Bằng: Kong, A, et al.
Được phát hành: (2009)