A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.
To identify new risk variants for cutaneous basal cell carcinoma, we performed a genome-wide association study of 16 million SNPs identified through whole-genome sequencing of 457 Icelanders. We imputed genotypes for 41,675 Illumina SNP chip-typed Icelanders and their relatives. In the discovery pha...
Main Authors: | Stacey, SN, Sulem, P, Jonasdottir, A, Masson, G, Gudmundsson, J, Gudbjartsson, D, Magnusson, O, Gudjonsson, SA, Sigurgeirsson, B, Thorisdottir, K, Ragnarsson, R, Benediktsdottir, K, Nexø, B, Tjønneland, A, Overvad, K, Rudnai, P, Gurzau, E, Koppova, K, Hemminki, K, Corredera, C, Fuentelsaz, V, Grasa, P, Navarrete, S, Fuertes, F, García-Prats, MD |
---|---|
格式: | Journal article |
语言: | English |
出版: |
2011
|
相似书籍
-
A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
由: Stacey, SN, et al.
出版: (2011) -
Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.
由: Rafnar, T, et al.
出版: (2009) -
A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer
由: Gudmundsson, J, et al.
出版: (2012) -
Parental origin of sequence variants associated with complex diseases.
由: Kong, A, et al.
出版: (2009) -
Parental origin of sequence variants associated with complex diseases
由: Kong, A, et al.
出版: (2009)