Competition between CTL narrows the immune response induced by prime-boost vaccination protocols.
Recombinant vaccines encoding strings of virus- or tumor-derived peptides and/or proteins are currently being designed for use against both cancer and infectious diseases. These vaccines aim to induce cytotoxic immune responses against several Ags simultaneously. We developed a novel tetramer-based...
Autores principales: | Palmowski, M, Choi, E, Hermans, I, Gilbert, S, Chen, J, Gileadi, U, Salio, M, Van Pel, A, Man, S, Bonin, E, Liljestrom, P, Dunbar, P, Cerundolo, V |
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Formato: | Journal article |
Lenguaje: | English |
Publicado: |
2002
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