Unprecedented regiocontrol using an aldolase I antibody.
Direct asymmetric aldol reactions at the less substituted carbon atom of unmodified unsymmetrical ketones are achieved in the presence of the commercially available aldolase I antibody 84G3 [Eq. (1)]. All the reactions proceeded with enantiomeric excesses greater than 94%. Both enantiomers are acces...
| Main Authors: | , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2002
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