Endotoxin signaling in human macrophages: signaling via an alternate mechanism.

Endotoxin signaling in human macrophages: signaling via an alternate mechanism.

Lipopolysaccharide (LPS) signals through Toll-like receptors (TLRs) in the course of sepsis, resulting in the release of inflammatory factors. In cell lines and murine models, parts of the signaling pathways involved have been elucidated with MyD88, Mal/TIRAP and IKK2 playing an important role in th...

Полное описание

Библиографические подробности
Главные авторы:	Sacre, S, Andreakos, E, Feldmann, M, Foxwell, B
Формат:	Journal article
Язык:	English
Опубликовано:	2004

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