EGF-coated gold nanoparticles provide an efficient nano-scale delivery system for the molecular radiotherapy of EGFR-positive cancer.
Purpose Radiolabeled antibodies and peptides hold promise for molecular radiotherapy but are often limited by a low payload resulting in inadequate delivery of radioactivity to tumour tissue and, therefore, modest therapeutic effect. We developed a facile synthetic method of radiolabeling indium-111...
Հիմնական հեղինակներ: | Song, L, Falzone, N, Vallis, K |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
Taylor and Francis
2016
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Նմանատիպ նյութեր
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EGF Functionalized Polymer-Coated Gold Nanoparticles Promote EGF Photostability and EGFR Internalization for Photothermal Therapy.
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Accumulation of 111In-Labelled EGF-Au-PEG Nanoparticles in EGFR-Positive Tumours is Enhanced by Co-administration of Targeting Ligand
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Հրապարակվել է: (2017) -
SPECT imaging and biodistribution studies of 111In-EGF-Au-PEG nanoparticles in vivo
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Հրապարակվել է: (2016) -
Comparative antiproliferative effects of (111)In-DTPA-hEGF, chemotherapeutic agents and gamma-radiation on EGFR-positive breast cancer cells.
: Chen, P, և այլն
Հրապարակվել է: (2002) -
111In-labeled EGF is selectively radiotoxic to human breast cancer cells overexpressing EGFR.
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Հրապարակվել է: (2000)