T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles

The immunological synapse is a molecular hub that facilitates the delivery of three activation signals, namely antigen, costimulation/corepression and cytokines, from antigen-presenting cells (APC) to T cells. T cells release a fourth class of signaling entities, trans-synaptic vesicles (tSV), to me...

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Bibliographic Details
Main Authors: Céspedes, PF, Jainarayanan, A, Fernández-Messina, L, Valvo, S, Saliba, DG, Kurz, E, Kvalvaag, A, Chen, L, Ganskow, C, Colin-York, H, Fritzsche, M, Peng, Y, Dong, T, Johnson, E, Siller-Farfán, JA, Dushek, O, Sezgin, E, Peacock, B, Law, A, Aubert, D, Engledow, S, Attar, M, Hester, S, Fischer, R, Sánchez-Madrid, F, Dustin, ML
Format: Journal article
Language:English
Published: Springer Nature 2022

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