Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture.

<p><strong>BACKGROUND:</strong> Repeated culture reduces within-sample Mycobacterium tuberculosis genetic diversity due to selection of clones suited to growth in culture and/or random loss of lineages, but it is not known to what extent omitting the culture step altogether alters...

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Manylion Llyfryddiaeth
Prif Awduron: Nimmo, C, Shaw, LP, Doyle, R, Williams, R, Brien, K, Burgess, C, Breuer, J, Balloux, F, Pym, AS
Fformat: Journal article
Iaith:English
Cyhoeddwyd: BioMed Central 2019