Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture.
<p><strong>BACKGROUND:</strong> Repeated culture reduces within-sample Mycobacterium tuberculosis genetic diversity due to selection of clones suited to growth in culture and/or random loss of lineages, but it is not known to what extent omitting the culture step altogether alters...
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
BioMed Central
2019
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