REACTION OF ADENINE WITH AN ALPHA-CHLOROOXETANE - AN APPROACH TO THE SYNTHESIS OF OXETANE NUCLEOSIDES

The reaction of adenine with 3,5-anhydro-5R-chloro-1,2-O- isopropylidenexylofuranose, a stable α-chlorooxetane, gives a mixture of the two epimers of 5-[9-adenyl]-3,5-anhydro- 1,2-O-isopropylidenexylofuranose; the structure of 5R-[9- adenyl)-3,5-anhydro-1,2-O-isopropylidenexylofuranose was establish...

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Main Authors: Fleet, G, Son, J, Vogt, K, Peach, J, Hamor, T
格式: Journal article
语言:English
出版: 1988