Type 2 diabetes transcription factor 7-like 2 (TCF7L2) risk alleles reduce beta-cell function and increase birth weight

Míreanna comhchosúla

• Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals.
  de réir: Freathy, R, et al.
  Foilsithe / Cruthaithe: (2007)
• Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.
  de réir: Groves, C, et al.
  Foilsithe / Cruthaithe: (2006)
• Pharmacogenetics in Type 2 diabetes: variation in TCF7L2 influences response to sulphonylureas
  de réir: Pearson, E, et al.
  Foilsithe / Cruthaithe: (2007)
• Type 2 diabetes risk alleles are associated with reduced size at birth.
  de réir: Freathy, R, et al.
  Foilsithe / Cruthaithe: (2009)
• TCF7L2: the biggest story in diabetes genetics since HLA?
  de réir: Zeggini, E, et al.
  Foilsithe / Cruthaithe: (2007)