A role for 5-HT in the action of antidepressant drugs.

Administration of antidepressant drugs to rodents appears to decrease 5-HT2 receptor function while transmission through postsynaptic 5-HT1 receptor synapses may be enhanced. Antidepressant drugs also alter 5-HT mechanisms in humans; some of these changes are congruent with effects noted in animal s...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur: Cowen, P
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 1990