A role for 5-HT in the action of antidepressant drugs.

Administration of antidepressant drugs to rodents appears to decrease 5-HT2 receptor function while transmission through postsynaptic 5-HT1 receptor synapses may be enhanced. Antidepressant drugs also alter 5-HT mechanisms in humans; some of these changes are congruent with effects noted in animal s...

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Bibliographic Details
Main Author: Cowen, P
Format: Journal article
Language:English
Published: 1990